Wuhan · China

Welcome to Liang Luo Group


●Xin, Y.; Fang, F.; Yue, Q.; Luo, Y.; Tian, S.; Cheng, L.; Wang, X.; Yang, X.; Luo, L.*; Meng, F.*, Microenvironment modulating nanogels by Shiitake-derived lentinan and a reactive oxygen species scavenging conjugated polymer for the treatment of Alzheimer’s disease. Nano Today 2024, 55,102178.

●Yin, M.; Zhao, L.; Liu, S.; Tian, S.; Meng, F.; Luo, L.*, Conjugation Length-Dependent Raman Scattering Intensity of Conjugated Polymers. Macromol Rapid Communication 2023, e2300412.

●Wang, H.; Li, Q.; Alam, P.*; Bai, H.*; Bhalla, V.*; Bryce, M. R.*; Cao, M.; Chen, C.; Chen, S.*; Chen, X.; Chen, Y.*; Chen, Z.*; Dang, D.*; Ding, D.*; Ding, S.; Duo, Y.*; Gao, M.*; He, W.; He, X.*; Hong, X.*; Hong, Y.*; Hu, J. J.; Hu, R.*; Huang, X.*; James, T. D.*; Jiang, X.*; Konishi, G. I.*; Kwok, R. T. K.*; Lam, J. W. Y.*; Li, C.; Li, H.; Li, K.*; Li, N.; Li, W. J.; Li, Y.*; Liang, X. J.*; Liang, Y.*; Liu, B.*; Liu, G.*; Liu, X.; Lou, X.*; Lou, X. Y.; Luo, L.*; McGonigal, P. R.*; Mao, Z. W.*; Niu, G.*; Owyong, T. C.; Pucci, A.*; Qian, J.*; Qin, A.*; Qiu, Z.*; Rogach, A. L.*; Situ, B.; Tanaka, K.*; Tang, Y.*; Wang, B.; Wang, D.*; Wang, J.*; Wang, W.; Wang, W. X.*; Wang, W. J.; Wang, X.; Wang, Y. F.; Wu, S.*; Wu, Y.; Xiong, Y.; Xu, R.; Yan, C.; Yan, S.; Yang, H. B.*; Yang, L. L.; Yang, M.; Yang, Y. W.*; Yoon, J.*; Zang, S. Q.*; Zhang, J.; Zhang, P.*; Zhang, T.; Zhang, X.*; Zhang, X.; Zhao, N.*; Zhao, Z.*; Zheng, J.*; Zheng, L.*; Zheng, Z.*; Zhu, M. Q.*; Zhu, W. H.*; Zou, H.; Tang, B. Z.*, Aggregation-Induced Emission (AIE), Life and Health. ACS Nano 2023, 17 (15), 14347-14405.

●Zhao, L.; Luo, L.*; Meng, F.*, Metal-mediated nanobody assemblies as potent alleviators of human islet amyloid polypeptide aggregation. Materials Chemistry Frontiers 2023, 7 (10), 2068-2077.

●Zhao, L.; Meng, F.; Li, Y.; Liu, S.; Xu, M.; Chu, F.; Li, C.; Yang, X.; Luo, L.*, Multivalent Nanobody Conjugate with Rigid, Reactive Oxygen Species Scavenging Scaffold for Multi-Target Therapy of Alzheimer's Disease. Adv Mater 2023, 35 (17), e2210879.

●Yin, M.; Chen, Y.; Liu, X.; Tian, S.*; Zhao, L.; Bai, Y.; Wang, H.; Lin, J.; Jiang, D.; Lei, Z.; Meng, F.; Tian, D.; Luo, L.*, Targeted Computed Tomography Visualization and Healing of Inflammatory Bowel Disease by Orally Delivered Bacterial-Flagella-Inspired Polydiiododiacetylene Nanofibers. Acs Nano 2023, 17 (4), 3873-3888.

●Wang, X.; Chen, Y.; Yang, X.; Cheng, L.; He, Z.; Xin, Y.; Huang, S.; Meng, F.; Zhang, P.*; Luo, L.*, Activation of ALOX12 by a multi-organelle-orienting photosensitizer drives ACSL4-independent cell ferroptosis. Cell Death Dis 2022, 13 (12), 1040.

●Zhang, D.; Tian, S.; Liu, Y.; Zheng, M.; Yang, X.; Zou, Y.*; Shi, B.*; Luo, L.*, Near infrared-activatable biomimetic nanogels enabling deep tumor drug penetration inhibit orthotopic glioblastoma. Nat Commun 2022, 13 (1), 6835.

●Yin, M.; Tong, J.; Meng, F.; Liu, C.; Liu, X.; Fang, F.; He, Z.; Qin, X.; Liu, C.; Ni, D.; Gao, Y.*; Liang, H.*; Zhang, X.*; Luo, L.*, Near-Infrared-II Activatable Symbiotic 2D Carbon–Clay Nanohybrids for Dual Imaging-Guided Combinational Cancer Therapy. Acs Appl Mater Inter 2022,14,49471-49482.

●Yue, Q.; Luo, L.*, Turning trash into treasure: Metal-free upcycling of polystyrene plastic waste to aromatics. Chem 2022, 8 (9), 2326-2329.

●Tian, S.; Lu, Y.; He, Z.; Yue, Q.; Zhuang, Z.; Wang, Y.; Meng, F.; Luo, L.*, Polydiacetylene-based poly-ion complex enabling aggregation-induced emission and photodynamic therapy dual turn-on for on-demand pathogenic bacteria elimination. Science China Chemistry 2022, 65 (9), 1782-1790.

●Zhang, Y.; Tian, S.; Huang, L.; Li, Y.; Lu, Y.; Li, H.; Chen, G.; Meng, F.; Liu, G. L.; Yang, X.; Tu, J.; Sun, C.; Luo, L.*, Reactive oxygen species-responsive and Raman-traceable hydrogel combining photodynamic and immune therapy for postsurgical cancer treatment. Nat Commun 2022, 13 (1), 4553.

●Lin, J.; Yin, M.; Liu, X.; Meng, F.; Luo, L.*, Nanomaterials Based on Functional Polymers for Sensitizing Cancer Radiotherapy. Macromol Rapid Commun 2022, 43 (18), e2200194.

●Li, M.; Tian, S.; Meng, F.; Yin, M.; Yue, Q.; Wang, S.; Bu, W.; Luo, L.*, Continuously Multiplexed Ultrastrong Raman Probes by Precise Isotopic Polymer Backbone Doping for Multidimensional Information Storage and Encryption. Nano Lett 2022, 22 (11), 4544-4551.

●Yin, M.; Liu, X.; Lei, Z.; Gao, Y.; Liu, J.; Tian, S.; Liang, Z.; Wang, Y.; Meng, F.; Luo, L.*, Precisely translating computed tomography diagnosis accuracy into therapeutic intervention by a carbon-iodine conjugated polymer. Nat Commun 2022, 13 (1), 2625.

●Zhao, L.; Wang, S.; Hu, Q.; Jia, H.; Xin, Y.; Luo, L.*; Meng, F.*, Conformation-reconstructed multivalent antibody mimic for amplified mitigation of human islet amyloid polypeptide amyloidogenesis. Nanoscale 2022, 14 (7), 2802-2815.

●Zhuang, Z.; Meng, F.; Luo, L.*, Naked-eye detection and sustainable removal of zinc ions in water by a conjugated polymer with ratiometric absorption. Organic Electronics 2021, 99,106347.

●He, Z.; Gao, Y.; Zhang, H.; Xue, Y.; Meng, F.; Luo, L.*, Mitochondrion-Anchored Photosensitizer with Near Infrared-I Aggregation-Induced Emission for Near Infrared-II Two-Photon Photodynamic Therapy. Adv Healthc Mater 2021, e2101056.

●Xin, Y.; Wang, S.; Liu, H.; Ke, H.; Tian, S.; Cao, Y.; Huang, Y.; Shang, Y.; Jia, H.; Su, L.; Yang, X.; Meng, F.*; Luo, L.*, Hierarchical Vitalization of Oligotyrosine in Mitigating Islet Amyloid Polypeptide Amyloidogenesis through Multivalent Macromolecules with Conformation-Restrained Nanobody Ligands. Acs Nano 2021,15,13319-13328. 

●Yue, Q.; He, X.; Yan, N.; Tian, S.; Liu, C.; Wang, W.-X.*; Luo, L.*; Tang, B. Z.*, Photodynamic control of harmful algal blooms by an ultra-efficient and degradable AIEgen-based photosensitizer. Chemical Engineering Journal 2021, 417,127890.

●Tian, S.; Yue, Q.; Liu, C.; Li, M.; Yin, M.; Gao, Y.; Meng, F.; Tang, B. Z.*; Luo, L.*, Complete Degradation of a Conjugated Polymer into Green Upcycling Products by Sunlight in Air. J Am Chem Soc 2021, 143 (27), 10054-10058.

●Wang, X.; Li, H.; Meng, F.*; Luo, L., Bioadhesive metal-phenolic nanoparticles for enhanced NIR imaging-guided locoregional photothermal/antiangiogenic therapy. J Mater Chem B 2021, 9 (23), 4710-4717.

●Huang, L.; Zhang, Y.; Li, Y.; Meng, F.; Li, H.; Zhang, H.; Tu, J.; Sun, C.*; Luo, L.*, Time-Programmed Delivery of Sorafenib and Anti-CD47 Antibody via a Double-Layer-Gel Matrix for Postsurgical Treatment of Breast Cancer. Nanomicro Lett 2021, 13 (1), 141.

●He, Z.; Tian, S.; Gao, Y.; Meng, F.*; Luo, L.*, Luminescent AIE Dots for Anticancer Photodynamic Therapy. Front Chem 2021, 9, 672917. 

●Xue, Y.; Gao, Y.; Meng, F.; Luo, L.*, Recent progress of nanotechnology-based theranostic systems in cancer treatments. Cancer Biol Med 2021,18(2),336-351. 

●Cao, Y.; He, Z.; Gao, Y.; Xin, Y.; Luo, L.; Meng, F.*, Boosting the Photodynamic Degradation of Islet Amyloid Polypeptide Aggregates Via a "Bait-Hook-Devastate" Strategy. ACS Appl Mater Interfaces 2021, 13(13),14911-14919.

●Fang, F.; Gao, Y.; Luo, L.*, Mitochondrion-anchoring AIEgen with Large Stokes Shift for Imaging-guided Photodynamic Therapy. Chemical Research in Chinese Universities 2021, 37 (1), 137-142.

● Liu, C.; Wang, X.; Liu, J.; Yue, Q.; Chen, S.; Lam, J. W. Y.; Luo, L.*; Tang, B. Z.*, Near-Infrared AIE Dots with Chemiluminescence for Deep-Tissue Imaging. Adv Mater 2020, e2004685.

● Nie, C.; Zhang, B.; Gao, Y.; Yin, M.; Yi, X.; Zhao, C.; Zhang, Y.; Luo, L.*; Wang, S.*, Thickness-Dependent Enhancement of Electronic Mobility of MoS2 Transistors via Surface Functionalization. The Journal of Physical Chemistry C 2020, 124 (31), 16943-16950.

● He, Z.; Gao, Y.; Zhang, H.; Wang, X.; Meng, F.; Luo, L.*; Tang, B. Z.*, Platinum-AIEgen coordination complex for imaging-guided annihilation of cisplatin-resistant cancer cells. Chem Commun (Camb) 2020, 56 (56), 7785-7788.

● Gao, Y.; Zhang, H.; He, Z.; Fang, F.; Wang, C.; Zeng, K.; Gao, S.; Meng, F.; Luo, L.*; Tang, B. Z.*, Multicationic AIEgens for unimolecular photodynamic theranostics and two-photon fluorescence bioimaging. Materials Chemistry Frontiers 2020, 4 (6), 1623-1633.

● Hou, Y.; Kurganskii, I.; Elmali, A.; Zhang, H.; Gao, Y.; Lv, L.; Zhao, J.*; Karatay, A.*; Luo, L.*; Fedin, M.*, Electronic coupling and spin-orbit charge transfer intersystem crossing (SOCT-ISC) in compact BDP-carbazole dyads with different mutual orientations of the electron donor and acceptor. J Chem Phys 2020, 152 (11), 114701.

● Wang, X.; Huang, L.; Zhang, Y.; Meng, F.*; Donoso, M.; Haskell, R.*; Luo, L.*, Tunable Two-Compartment On-Demand Sustained Drug Release Based on Lipid Gels. J Pharm Sci 2020, 109 (2), 1059-1067.

● Fang, F.; Meng, F.; Luo, L.*, Recent advances on polydiacetylene-based smart materials for biomedical applications. Materials Chemistry Frontiers 2020, 4 (4), 1089-1104.

● Wang, Z.; Ivanov, M.; Gao, Y.; Bussotti, L.; Foggi, P.; Zhang, H.; Russo, N.; Dick, B.; Zhao, J.*; Di Donato, M.*; Mazzone, G.*; Luo, L.*; Fedin, M.*, Spin-Orbit Charge-Transfer Intersystem Crossing (ISC) in Compact Electron Donor-Acceptor Dyads: ISC Mechanism and Application as Novel and Potent Photodynamic Therapy Reagents. Chemistry 2020, 26 (5), 1091-1102.

● Wang, X.; Tong, J.; He, Z.; Yang, X.; Meng, F.*; Liang, H.*; Zhang, X.*; Luo, L.*, Paclitaxel-Potentiated Photodynamic Theranostics for Synergistic Tumor Ablation and Precise Anticancer Efficacy Monitoring. ACS Appl Mater Interfaces 2020, 12 (5), 5476-5487.

● Tian, S.; Li, H.; Li, Z.; Tang, H.; Yin, M.; Chen, Y.; Wang, S.; Gao, Y.; Yang, X.; Meng, F.*; Lauher, J. W.*; Wang, P.*; Luo, L.*, Polydiacetylene-based ultrastrong bioorthogonal Raman probes for targeted live-cell Raman imaging. Nature Communications 2020, 11 (1), 81.

● Gao, Y.; He, Z.; He, X.; Zhang, H.; Weng, J.; Yang, X.; Meng, F.*; Luo, L.*; Tang, B. Z.*, Dual-Color Emissive AIEgen for Specific and Label-Free Double-Stranded DNA Recognition and Single-Nucleotide Polymorphisms Detection. J Am Chem Soc 2019, 141 (51), 20097-20106.

● Huang, L.; Li, Y.; Du, Y.; Zhang, Y.; Wang, X.; Ding, Y.; Yang, X.; Meng, F.; Tu, J.*; Luo, L.*; Sun, C.*, Mild photothermal therapy potentiates anti-PD-L1 treatment for immunologically cold tumors via an all-in-one and all-in-control strategy. Nat Commun 2019, 10 (1), 4871.

●DeCicco, R. C.#; Luo, L.#; Goroff, N. S., Exploiting Unsaturated Carbon-Iodine Compounds for the Preparation of Carbon-Rich Materials. Acc Chem Res 2019, 52 (8), 2080-2089.

●He, X.; Xiong, L. H.; Zhao, Z.; Wang, Z.; Luo, L.; Lam, J. W. Y.; Kwok, R. T. K.; Tang, B. Z., AIE-based theranostic systems for detection and killing of pathogens. Theranostics 2019, 9 (11), 3223-3248.

●Gao, Y.; Wang, X.; He, X.; He, Z.; Yang, X.; Tian, S.; Meng, F.*; Ding, D.*; Luo, L.*; Tang, B. Z.*, A Dual‐Functional Photosensitizer for Ultraefficient Photodynamic Therapy and Synchronous Anticancer Efficacy Monitoring. Advanced Functional Materials 2019, 29 (32),1902673.

●Zhao, L.; Xin, Y.; Li, Y.; Yang, X.; Luo, L.*; Meng, F.*, Ultraeffective Inhibition of Amyloid Fibril Assembly by Nanobody–Gold Nanoparticle Conjugates. Bioconjugate Chem 2019, 30 (1), 29-33.

●Xin, Y.; Zhang, H.; Hu, Q.; Tian, S.; Wang, C.; Luo, L.*; Meng, F.*, Oligotyrosines Inhibit Amyloid Formation of Human Islet Amyloid Polypeptide in a Tyrosine-Number-Dependent Manner. Acs Biomater Sci Eng 2019, 5 (2), 1092-1099.

●Wang, Z.; Gao, Y.; Hussain, M.; Kundu, S.; Rane, V.; Hayvali, M.; Yildiz, E. A.; Zhao, J.*; Yaglioglu, H. G.*; Das, R.*; Luo, L.*; Li, J.*, Efficient Radical-Enhanced Intersystem Crossing in an NDI-TEMPO Dyad: Photophysics, Electron Spin Polarization, and Application in Photodynamic Therapy. Chemistry – A European Journal 2018, 24 (70), 18663-18675.

●Xin, Y.; Wang, X.; Luo, L.*; Meng, F.*, Conformation-Dependent Manipulation of Human Islet Amyloid Polypeptide Fibrillation by Shiitake-Derived Lentinan. ACS Appl Mater Interfaces 2018, 10 (37), 31069-31079.

●Xin, Y.; Yin, M.; Zhao, L.; Meng, F.; Luo, L.*, Recent progress on nanoparticle-based drug delivery systems for cancer therapy. Cancer Biol Med 2017, 14 (3), 228-241.

Luo, L.;  Balhorn, L.;  Vlaisavljevich, B.;  Ma, D.;  Gagliardi, L.; Frisbie, C. D., Hopping Transport and Rectifying Behavior in Long Donor–Acceptor Molecular Wires. The Journal of Physical Chemistry C 2014, 118 (46), 26485-26497.

Hu, J.-X.;  Shang, H.;  Wang, J.-G.;  Luo, L.;  Xiao, Q.;  Zhong, Y.-J.; Zhu, W.-D., Highly Enhanced Selectivity and Easy Regeneration for the Separation of CO2 over N2 on Melamine-Based Microporous Organic Polymers. Industrial & Engineering Chemistry Research 2014, 53 (29), 11828-11837.

Luo, L.;  Resch, D.;  Wilhelm, C.;  Young, C. N.;  Halada, G. P.;  Gambino, R. J.;  Grey, C. P.; Goroff, N. S., Room-Temperature Carbonization of Poly(diiododiacetylene) by Reaction with Lewis Bases. Journal of the American Chemical Society 2011, 133 (48), 19274-19277.

Luo, L.;  Benameur, A.;  Brignou, P.;  Choi, S. H.;  Rigaut, S.; Frisbie, C. D., Length and Temperature Dependent Conduction of Ruthenium-Containing Redox-Active Molecular Wires. The Journal of Physical Chemistry C 2011, 115 (40), 19955-19961.

Luo, L.;  Wilhelm, C.;  Young, C. N.;  Grey, C. P.;  Halada, G. P.;  Xiao, K.;  Ivanov, I. N.;  Howe, J. Y.;  Geohegan, D. B.; Goroff, N. S., Characterization and Carbonization of Highly Oriented Poly(diiododiacetylene) Nanofibers. Macromolecules 2011, 44 (8), 2626-2631.

Luo, L.;  Choi, S. H.; Frisbie, C. D., Probing Hopping Conduction in Conjugated Molecular Wires Connected to Metal Electrodes. Chem Mater 2011, 23 (3), 631-645.

Luo, L.; Frisbie, C. D., Length-Dependent Conductance of Conjugated Molecular Wires Synthesized by Stepwise “Click” Chemistry. Journal of the American Chemical Society 2010, 132 (26), 8854-8855.

Luo, L.;  Wilhelm, C.;  Sun, A.;  Grey, C. P.;  Lauher, J. W.; Goroff, N. S., Poly(diiododiacetylene): Preparation, Isolation, and Full Characterization of a Very Simple Poly(diacetylene). Journal of the American Chemical Society 2008, 130 (24), 7702-7709.

Wilhelm, C.;  Boyd, S. A.;  Chawda, S.;  Fowler, F. W.;  Goroff, N. S.;  Halada, G. P.;  Grey, C. P.;  Lauher, J. W.;  Luo, L.;  Martin, C. D.;  Parise, J. B.;  Tarabrella, C.; Webb, J. A., Pressure-Induced Polymerization of Diiodobutadiyne in Assembled Cocrystals. Journal of the American Chemical Society 2008, 130 (13), 4415-4420.