Wuhan · China

Welcome to Liang Luo Group

P I

● Professor, Huazhong University of Science and Technology (2015-now)

● Research Investigator, Bristol-Myers Squibb Company, USA (2012-2015)

● Postdoc, University of Minnesota, USA (2009-2012)







● Ph.D, The State University of New York at Stony Brook, USA (2004-2009)

● M.S., Nankai University (2001-2004)

● B.S., Nankai University (1997-2001)

AWARDS AND GRANTS
● National Basic Research Program of China (2020)
● National Science Foundation of China (2018)
● National Basic Research Program of China (2018)
​● Young Thousand Talents Plan of China (2015)

PUBLIC SERVICE
● Chairman, Department of Nanomedicine and Biopharmaceutics, College of Life Science and Technology
● Vice Director, Youth Committee of Nanooncology, Chinese Anti Cancer Association (2018)
● President, Connecticut Chapter, SINO-America Pharmaceutical Professionals Association (2016)

● Xin, Y.; Wang, S.; Liu, H.; Ke, H.; Tian, S.; Cao, Y.; Huang, Y.; Shang, Y.; Jia, H.; Su, L.; Yang, X.; Meng, F.*; Luo, L.*; “Hierarchical Vitalization of Oligotyrosine in Mitigating Islet Amyloid Polypeptide Amyloidogenesis through Multivalent Macromolecules with Conformation-Restrained Nanobody Ligands”, ACS Nano, 2021
● Tian, S.; Yue, Q.; Liu, C.; Li, M.; Yin, M.; Gao, Y.; Meng, F.; Tang, B.*; Luo, L.* “Complete Degradation of a Conjugated Polymer into Green Upcycling Products by Sunlight in Air”, Journal of the American Chemical Society, 2021, 143, 27, 10054–10058
● Yue, Q.; He, X.; Yan, N.; Tian, S.; Liu, C.; Wang, W.-X.; Luo, L.; Tang, B. Z., Photodynamic control of harmful algal blooms by an ultra-efficient and degradable AIEgen-based photosensitizer. Chemical Engineering Journal 2021, 417.
● Huang, L.; Zhang, Y.; Li, Y.; Meng, F.; Li, H.; Zhang, H.; Tu, J.; Sun, C.; Luo, L., Time-Programmed Delivery of Sorafenib and Anti-CD47 Antibody via a Double-Layer-Gel Matrix for Postsurgical Treatment of Breast Cancer. Nanomicro Lett 2021, 13 (1), 141.
● Xue, Y.; Gao, Y.; Meng, F.; Luo, L., Recent progress of nanotechnology-based theranostic systems in cancer treatments. Cancer Biol Med 2021.
● Cao, Y.; He, Z.; Gao, Y.; Xin, Y.; Luo, L.; Meng, F., Boosting the Photodynamic Degradation of Islet Amyloid Polypeptide Aggregates Via a "Bait-Hook-Devastate" Strategy. ACS Appl Mater Interfaces 2021, 13(13),14911-14919.
● Fang, F.; Gao, Y.; Luo, L., Mitochondrion-anchoring AIEgen with Large Stokes Shift for Imaging-guided Photodynamic Therapy. Chemical Research in Chinese Universities 2021, 37 (1), 137-142.
● Liu, C.; Wang, X.; Liu, J.; Yue, Q.; Chen, S.; Lam, J. W. Y.; Luo, L.; Tang, B. Z., Near-Infrared AIE Dots with Chemiluminescence for Deep-Tissue Imaging. Adv Mater 2020, e2004685:1-6.
● He, Z.; Gao, Y.; Zhang, H.; Wang, X.; Meng, F.; Luo, L.; Tang, B. Z., Platinum-AIEgen coordination complex for imaging-guided annihilation of cisplatin-resistant cancer cells. Chem Commun (Camb) 2020, 56 (56), 7785-7788.
● Gao, Y.; Zhang, H.; He, Z.; Fang, F.; Wang, C.; Zeng, K.; Gao, S.; Meng, F.; Luo, L.; Tang, B. Z., Multicationic AIEgens for unimolecular photodynamic theranostics and two-photon fluorescence bioimaging. Materials Chemistry Frontiers 2020, 4 (6), 1623-1633.
● Wang, X.; Huang, L.; Zhang, Y.; Meng, F.; Donoso, M.; Haskell, R.; Luo, L., Tunable Two-Compartment On-Demand Sustained Drug Release Based on Lipid Gels. J Pharm Sci 2020, 109 (2), 1059-1067.
● Fang, F.; Meng, F.; Luo, L., Recent advances on polydiacetylene-based smart materials for biomedical applications. Materials Chemistry Frontiers 2020, 4 (4), 1089-1104.
● Wang, X.; Tong, J.; He, Z.; Yang, X.; Meng, F.; Liang, H.; Zhang, X.; Luo, L., Paclitaxel-Potentiated Photodynamic Theranostics for Synergistic Tumor Ablation and Precise Anticancer Efficacy Monitoring. ACS Appl Mater Interfaces 2020, 12 (5), 5476-5487.
● Tian, S.; Li, H.; Li, Z.; Tang, H.; Yin, M.; Chen, Y.; Wang, S.; Gao, Y.; Yang, X.; Meng, F.; Lauher, J. W.; Wang, P.; Luo, L., Polydiacetylene-based ultrastrong bioorthogonal Raman probes for targeted live-cell Raman imaging. Nature Communications 2020, 11 (1), 81.
● Gao, Y.; He, Z.; He, X.; Zhang, H.; Weng, J.; Yang, X.; Meng, F.; Luo, L.; Tang, B. Z., Dual-Color Emissive AIEgen for Specific and Label-Free Double-Stranded DNA Recognition and Single-Nucleotide Polymorphisms Detection. J Am Chem Soc 2019, 141 (51), 20097-20106.
● Huang, L.; Li, Y.; Du, Y.; Zhang, Y.; Wang, X.; Ding, Y.; Yang, X.; Meng, F.; Tu, J.; Luo, L.; Sun, C., Mild photothermal therapy potentiates anti-PD-L1 treatment for immunologically cold tumors via an all-in-one and all-in-control strategy. Nature Communications 2019, 10 (1).
● Wang, Z.; Ivanov, M.; Gao, Y.; Bussotti, L.; Foggi, P.; Zhang, H.; Russo, N.; Dick, B.; Zhao, J.; Di Donato, M.; Mazzone, G.; Luo, L.; Fedin, M., Spin-Orbit Charge Transfer Intersystem Crossing (ISC) in Compact Electron Donor-Acceptor Dyads: ISC Mechanism and Application as Novel and Potent Photodynamic Therapy Reagents. Chemistry-A European Journal 2019.
● DeCicco, R. C.; Luo, L.; Goroff, N. S., Exploiting Unsaturated Carbon-Iodine Compounds for the Preparation of Carbon-Rich Materials. Acc Chem Res 2019, 52 (8), 2080-2089.
● He, X.; Xiong, L. H.; Zhao, Z.; Wang, Z.; Luo, L.; Lam, J. W. Y.; Kwok, R. T. K.; Tang, B. Z., AIE-based theranostic systems for detection and killing of path-ogens. Theranostics 2019, 9 (11), 3223-3248.
● Gao, Y.; Wang, X.; He, X.; He, Z.; Yang, X.; Tian, S.; Meng, F.; Ding, D.; Luo, L.; Tang, B. Z., A Dual‐Functional Photosensitizer for Ultraefficient Photodyna-mic Therapy and Synchronous Anticancer Efficacy Monitoring. Advanced Functional Materials 2019, 29 (32).
● Xin, Y.; Zhang, H.; Hu, Q.; Tian, S.; Wang, C.; Luo, L.; Meng, F., Oligotyrosines Inhibit Amyloid Formation of Human Islet Amyloid Polypeptide in a Tyrosine-Number-Dependent Manner. Acs Biomater Sci Eng 2019, 5 (2), 1092-1099.
● Zhao, L.; Xin, Y.; Li, Y.; Yang, X.; Luo, L.; Meng, F., Ultraeffective Inhibition of Amyloid Fibril Assembly by Nanobody–Gold Nanoparticle Conjugates. Bioconju-gate Chem 2019, 30 (1), 29-33.
● Xin, Y.; Wang, X.; Luo, L.; Meng, F., Conformation-Dependent Manipulation of Human Islet Amyloid Polypeptide Fibrillation by Shiitake-Derived Lentinan. ACS Appl Mater Interfaces 2018, 10 (37), 31069-31079.
● Wang, Z.; Gao, Y.; Hussain, M.; Kundu, S.; Rane, V.; Hayvali, M.; Yildiz, E. A.; Zhao, J.; Yaglioglu, H. G.; Das, R.; Luo, L.; Li, J., Efficient Radical-Enhanced In-tersystem Crossing in an NDI-TEMPO Dyad: Photophysics, Electron Spin Polarization, and Application in Photodynamic Therapy. Chemistry – A European Journal 2018, 24 (70), 18663-18675.
● Xin, Y.; Yin, M.; Zhao, L.; Meng, F.; Luo, L., Recent progress on nanoparticle-based drug delivery systems for cancer therapy. Cancer Biol Med 2017, 14 (3), 228-241.
● Hu, J.-X.; Shang, H.; Wang, J.-G.; Luo, L.; Xiao, Q.; Zhong, Y.-J.; Zhu, W.-D., Highly Enhanced Selectivity and Easy Regeneration for the Separation of CO2 over N2 on Melamine-Based Microporous Organic Polymers. Industrial & Engineering Chemistry Research 2014, 53 (29), 11828-11837.
● Luo, L.; Benameur, A.; Brignou, P.; Choi, S. H.; Rigaut, S.; Frisbie, C. D., Length and Temperature Dependent Conduction of Ruthenium-Containing Redox-Active Molecular Wires. The Journal of Physical Chemistry C 2011, 115 (40), 19955-19961.
● Luo, L.; Choi, S. H.; Frisbie, C. D., Probing Hopping Conduction in Conjugated Molecular Wires Connected to Metal Electrodes. Chem Mater 2011, 23 (3), 631-645.
● Luo, L.; Resch, D.; Wilhelm, C.; Young, C. N.; Halada, G. P.; Gambino, R. J.; Grey, C. P.; Goroff, N. S., Room-Temperature Carbonization of Poly(diiododiacet-ylene) by Reaction with Lewis Bases. Journal of the American Chemical Society 2011, 133 (48), 19274-19277.
● Luo, L.; Wilhelm, C.; Young, C. N.; Grey, C. P.; Halada, G. P.; Xiao, K.; Ivanov, I. N.; Howe, J. Y.; Geohegan, D. B.; Goroff, N. S., Characterization and Carbon-ization of Highly Oriented Poly(diiododiacetylene) Nanofibers. Macromolecules 2011, 44 (8), 2626-2631.
● Luo, L.; Frisbie, C. D., Length-Dependent Conductance of Conjugated Molecular Wires Synthesized by Stepwise “Click” Chemistry. Journal of the American Ch-emical Society 2010, 132 (26), 8854-8855.
● Luo, L.; Wilhelm, C.; Sun, A.; Grey, C. P.; Lauher, J. W.; Goroff, N. S., Poly(diiododiacetylene): Preparation, Isolation, and Full Characterization of a Very Sim-ple Poly(diacetylene). Journal of the American Chemical Society 2008, 130 (24), 7702-7709.
● Wilhelm, C.; Boyd, S. A.; Chawda, S.; Fowler, F. W.; Goroff, N. S.; Halada, G. P.; Grey, C. P.; Lauher, J. W.; Luo, L.; Martin, C. D.; Parise, J. B.; Tarabrella, C.; Webb, J. A., Pressure-Induced Polymerization of Diiodobutadiyne in Assembled Cocrystals. Journal of the American Chemical Society 2008, 130 (13), 4415-4420.

Prof. Liang Luo

● Associate Professor, HUST (2016-now)
● Postdoctor, Rensselaer Polytechnic Institute, USA (2013-2015)



● Ph.D, The State University of New York at Stony Brook, USA (2005-2010)
● Master, Nankai University (2001-2004)
● B. Sc., Tianjin University of Science and Technology (1997-2001)

HONORS AND AWARDS
​● The National Natural Science Foundation of China (2019)

● Maria Tzamarioudaki Memorial Award for Outstanding Doctoral Student, State University of New York at Stony Brook (2009-2010)

● Fluorescent Analogs of The Islet Amyloid Polypeptide, US  PATENT & TRADEMARK OFFICE, 20100021390 (2010)

● Protein Misfolding Diseases: Current and Emerging Principles and Therapies

● Huang, L.; Zhang, Y.; Li, Y.; Meng, F.; Li, H.; Zhang, H.; Tu, J.; Sun, C.; Luo, L., Time-Programmed Delivery of Sorafenib and Anti-CD47 Antibody via a Double-Layer-Gel Matrix for Postsurgical Treatment of Breast Cancer. Nanomicro Lett 2021, 13 (1), 141.
● Xue, Y.; Gao, Y.; Meng, F.; Luo, L., Recent progress of nanotechnology-based theranostic systems in cancer treatments. Cancer Biol Med 2021.
● Cao, Y.; He, Z.; Gao, Y.; Xin, Y.; Luo, L.; Meng, F., Boosting the Photodynamic Degradation of Islet Amyloid Polypeptide Aggregates Via a "Bait-Hook-Devastate" Strategy. ACS Appl Mater Interfaces 2021, 13(13),14911-14919.
● Wang, X.; Tong, J.; He, Z.; Yang, X.; Meng, F.; Liang, H.; Zhang, X.; Luo, L., Paclitaxel-Potentiated Photodynamic Theranostics for Synergistic Tumor Ablation and Precise Anticancer Efficacy Monitoring. ACS Appl Mater Interfaces 2020, 12 (5), 5476-5487.
● He, Z.; Gao, Y.; Zhang, H.; Wang, X.; Meng, F.; Luo, L.; Tang, B. Z., Platinum-AIEgen coordination complex for imaging-guided annihilation of cisplatin-resistant cancer cells. Chem Commun (Camb) 2020, 56 (56), 7785-7788.
● Gao, Y.; Zhang, H.; He, Z.; Fang, F.; Wang, C.; Zeng, K.; Gao, S.; Meng, F.; Luo, L.; Tang, B. Z., Multicationic AIEgens for unimolecular photodynamic theranostics and two-photon fluorescence bioimaging. Materials Chemistry Frontiers 2020, 4 (6), 1623-1633.
● Wang, X.; Huang, L.; Zhang, Y.; Meng, F.; Donoso, M.; Haskell, R.; Luo, L., Tunable Two-Compartment On-Demand Sustained Drug Release Based on Lipid Gels. J Pharm Sci 2020, 109 (2), 1059-1067.
● Fang, F.; Meng, F.; Luo, L., Recent advances on polydiacetylene-based smart materials for biomedical applications. Materials Chemistry Frontiers 2020, 4 (4), 1089-1104.
● Wang, X.; Tong, J.; He, Z.; Yang, X.; Meng, F.; Liang, H.; Zhang, X.; Luo, L., Paclitaxel-Potentiated Photodynamic Theranostics for Synergistic Tumor Ablation and Precise Anticancer Efficacy Monitoring. ACS Appl Mater Interfaces 2020, 12 (5), 5476-5487.
● Tian, S.; Li, H.; Li, Z.; Tang, H.; Yin, M.; Chen, Y.; Wang, S.; Gao, Y.; Yang, X.; Meng, F.; Lauher, J. W.; Wang, P.; Luo, L., Polydiacetylene-based ultrastrong bioorthogonal Raman probes for targeted live-cell Raman imaging. Nat Commun 2020, 11 (1), 81.
● Huang, L.; Li, Y.; Du, Y.; Zhang, Y.; Wang, X.; Ding, Y.; Yang, X.; Meng, F.; Tu, J.; Luo, L.; Sun, C., Mild photothermal therapy potentiates anti-PD-L1 treatment for immunologically cold tumors via an all-in-one and all-in-control strategy. Nature Communications 2019, 10 (1).
● Gao, Y.; He, Z.; He, X.; Zhang, H.; Weng, J.; Yang, X.; Meng, F.; Luo, L.; Tang, B. Z., Dual-Color Emissive AIEgen for Specific and Label-Free Double-Stranded DNA Recognition and Single-Nucleotide Polymorphisms Detection. J Am Chem Soc 2019, 141 (51), 20097-20106.
● Gao, Y.; Wang, X.; He, X.; He, Z.; Yang, X.; Tian, S.; Meng, F.; Ding, D.; Luo, L.; Tang, B. Z., A Dual‐Functional Photosensitizer for Ultraefficient Photodyna-mic Therapy and Synchronous Anticancer Efficacy Monitoring. Advanced Functional Materials 2019, 29 (32).
● Xin, Y.; Zhang, H.; Hu, Q.; Tian, S.; Wang, C.; Luo, L.; Meng, F., Oligotyrosines Inhibit Amyloid Formation of Human Islet Amyloid Polypeptide in a Tyrosine-Number-Dependent Manner. Acs Biomater Sci Eng 2019, 5 (2), 1092-1099.
● Zhao, L.; Xin, Y.; Li, Y.; Yang, X.; Luo, L.; Meng, F., Ultraeffective Inhibition of Amyloid Fibril Assembly by Nanobody–Gold Nanoparticle Conjugates. Bioconju-gate Chem 2019, 30 (1), 29-33.
● Xin, Y.; Wang, X.; Luo, L.; Meng, F., Conformation-Dependent Manipulation of Human Islet Amyloid Polypeptide Fibrillation by Shiitake-Derived Lentinan. ACS Appl Mater Interfaces 2018, 10 (37), 31069-31079.
● Xin, Y.; Yin, M.; Zhao, L.; Meng, F.; Luo, L., Recent progress on nanoparticle-based drug delivery systems for cancer therapy. Cancer Biol Med 2017, 14 (3), 228-241.
● Christine C. Lee, Mark Julian, Kathryn Tiller, Fanling Meng, Sarah DuConge, Rehana Akter, Daniel Raleigh, Peter M Tessier. ;Design and optimization of  anti-amyloid domain antibodies specific for beta-Amyloid and islet amyloid polypeptide; (2016) Journal of Biological Chemistry  291,2858-2873.
● Fanling Meng, Andisheh Abedini, and Daniel P. Raleigh ;Combination of Kinetically Selected Inhibitors in Trans Leads to Highly Effective Inhibition of Amyloid F-ormation;(2010) Journal of the American Chemical Society, 132, 14340-14342.
● Fanling Meng, Andisheh Abedini, Annette Plesner, Katherine J. Potter, C. Bruce Verchere and Daniel P. Raleigh. “The Flavanol (-)-Epigallocatechin 3-Gal-late Inhibits Amyloid Formation by Islet Amyloid Polypeptide, Disaggregates Amyloid Fibrils, and Protects Cultured Cells against IAPP-Induced Toxicity; (2010) Bi-ochemisry, 49, 8127-8133.
● Fanling Meng, Andisheh Abedini, Annette Plesner, Katherine J. Potter, C. Bruce Verchere and Daniel P. Raleigh.;Sulfated Triphenyl Methane Derivatives are Po-tent Inhibitors of Amyloid Formation by Human Islet Amyloid Polypeptide and Protect against the Toxic Effect of Amyloid Formation; (2010) Journal of Molecular Biology, 400, 555-566.

Prof. Fanling Meng

POSTDOC

EDUCATION AND RESEARCH EXPERIENCE
● Postdoc, HUST (2017-now)


● Ph.D, University of Science and Technology of China (2011-2017)
● B. Sc., University of Science and Technology of China (2007-2011)

PUBLICATIONS
●  Tian, S.; Yue, Q.; Liu, C.; Li, M.; Yin, M.; Gao, Y.; Meng, F.; Tang, B.*; Luo, L.* “Complete Degradation of a Conjugated Polymer into Green Upcycling Products by Sunlight in Air”, Journal of the American Chemical Society, 2021, 143, 27, 10054–10058

● Tian, S.; Li, H.; Li, Z.; Tang, H.; Yin, M.; Chen, Y.; Wang, S.; Gao, Y.; Yang, X.; Meng, F.; Lauher, J. W.; Wang, P.; Luo, L., Polydiacetylene-based ultrastrong bioorthogonal Raman probes for targeted live-cell Raman imaging. Nat Commun 2020, 11 (1), 81.

● Gao, Y.; Wang, X.; He, X.; He, Z.; Yang, X.; Tian, S.; Meng, F.; Ding, D.; Luo, L.; Tang, B. Z., A Dual‐Functional Photosensitizer for Ultraefficient Photodynamic Therapy and Synchronous Anticancer Efficacy Monitoring. Advanced Functional Materials 2019, 29 (32),1902673.

● Xin, Y.; Zhang, H.; Hu, Q.; Tian, S.; Wang, C.; Luo, L.; Meng, F., Oligotyrosines Inhibit Amyloid Formation of Human Islet Amyloid Polypeptide in a Tyrosine-Number-Dependent Manner. Acs Biomater Sci Eng 2019, 5 (2), 1092-1099.

● Tian, Sidan; Liu, Guhuan; Wang, Xiaorui; Zhang, Guoying; Hu,Jinming, pH-Responsive Tumor-Targetable Theranostic Nanovectors Based on Core Crosslinked(CCL) Micelles with Fluorescence and Magnetic Resonance (MR) Dual Imaging Modalities and Drug Delivery Performance , POLYMERS, 2016.6, 8(6): 226.

● Tian, Sidan; Liu, Guhuan; Wang, Xiaorui; Wu, Tao; Yang, Jinxian; Ye,Xiaodong; Zhang, Guoying; Hu, Jin-ming; Liu, Shiyong, pHRegulated Reversible Transition Between Polyion Complexes (PIC) and Hydrogen-Bon-ding Complexes (HBC)with Tunable Aggregation-Induced Emission , ACS APPLIED MATERIALS & INTERFACE-S, 2016.2.17, 8(6): 3693~3702.

● Li, Yamin; Hu, Xianglong; Tian, Sidan; Li, Yang; Zhang, Guoqing; Zhang,Guoying; Liu, Shiyong, Polyion c-omplex micellar nanoparticles for integrated fluorometric detection and bacteria inhibition in aqueous media ,BIOMATERIALS, 2014.2, 35(5): 1618~1626.

Ph. D, Sidan Tian

EDUCATION AND RESEARCH EXPERIENCE
● Postdoc, HUST (2020-now)


● Ph.D, Sichuan University (2015-2020)
● B. Sc., Shandong Normal Unviersity (2011-2015)

PUBLICATIONS

● Li, Mengyang; Li, Kun; Liu, Yanhong; Zhang, Hong; Yu, Kangkang; Liu, Xin; Yu, Xiaoqi, Mitochondria-Immobilized Fluorescent Probe for the Detection of Hypochlorite in Living Cells, Tissues and Zebrafishes, Anal. Chem., 2020, 92, 3262−3269.

● Li, Mengyang; Liu, Yanhong; Li, Kun; Zhang, Hong; Shi, Lei; Liu, Xinyao; Yu, Kangkang; Yu, Xiaoqi, Mitochondria-nucleolus migration fluorescent probe for monitoring of mitochondrial membrane potential and identification of cell apoptosis, Anal. Methods, 2019, 11, 5750–5754.

● Li, Mengyang; Cui, Pengcheng; Li, Kun; Feng, Jiahui; Zou, Mingming; Yu, Xiaoqi, Dual-site fluorescent probe for highly selective and sensitive detection of sulfite and biothiols, Chin. Chem. Lett., 2018, 29, 992–994.

Ph. D, Mengyang Li

EDUCATION AND RESEARCH EXPERIENCE
● Postdoc, HUST (2020-now)

● Ph.D, University Medical Center Groningen (2015-2020)

● Master, China Agricultural University (2013-2015)

● B. Sc., Huazhong Agricultural University (2009-2013)

PUBLICATIONS
● L. Cheng, C. Kong, W. Wang, A. Groeneveld, A. Nauta, M.R. Groves, M.B.G. Kiewiet, P. de Vos, The Human Milk Oligosaccharides 3-FL, Lacto-N-Neotetraose, and LDFT Attenuate Tumor Necrosis Factor-α Induced Inflammation in Fetal Intestinal Epithelial Cells In Vitro through Shedding or Interacting with Tumor Necrosis Factor Receptor 1, Mol. Nutr. Food Res. 2021, 65, 4.
● L. Cheng, M.B.G. Kiewiet, M.J. Logtenberg, A. Groeneveld, A. Nauta, H.A. Schols, M.T.C. Walvoort, H.J.M. Harmsen, P. de Vos, Effects of Different Human Milk Oligosaccharides on Growth of Bifidobacteria in Monoculture and Co-culture With Faecalibacterium prausnitzii, Front. Microbiol. 2020, 11, 1.
● L. Cheng, R. Akkerman, C. Kong, M.T.C. Walvoort, P. de Vos, More than sugar in the milk: human milk oligosaccharides as essential bioactive molecules in breast milk and current insight in beneficial effects, Crit. Rev. Food Sci. Nutr. 2020.
● L. Cheng, C. Kong, M.T.C. Walvoort, M.M. Faas, P. de Vos, Human Milk Oligosaccharides Differently Modulate Goblet Cells Under Homeostatic, Proinflammatory Conditions and ER Stress, Mol. Nutr. Food Res. 2020, 64, 1900976.
● L. Cheng, M.B.G. Kiewiet, A. Groeneveld, A. Nauta, P. de Vos, Human milk oligosaccharides and its acid hydrolysate LNT2 show immunomodulatory effects via TLRs in a dose and structure-dependent way, J. Funct. Foods. 2019, 59, 174.
● C. Kong, L. Cheng, G. Krenning, J. Fledderus, B.J. De Haan, M.T.C. Walvoort, P. De Vos, Human milk oligosaccharides mediate the crosstalk between intestinal epithelial Caco-2 cells and lactobacillus plantarum WCFS1 in an in vitro model with intestinal peristaltic shear force, J. Nutr. 2020, 150, 2077.
C. Ren, L. Cheng, Y. Sun, Q. Zhang, B.J. de Haan, H. Zhang, M.M. Faas, P. de Vos, Lactic acid bacteria secrete toll like receptor 2 stimulating and macrophage immunomodulating bioactive factors, J. Funct. Foods. 2020, 66.
● C. Kong, M. Elderman, L. Cheng, B.J. de Haan, A. Nauta, P. de Vos, Modulation of Intestinal Epithelial Glycocalyx Development by Human Milk Oligosaccharides and Non-Digestible Carbohydrates, Mol. Nutr. Food Res. 2019.

Ph. D, Lianghui Cheng

EDUCATION AND RESEARCH EXPERIENCE
● Postdoc, HUST (2021-now)


● Ph.D, Wuhan University (2012-2017)
● B. Sc, huanggang normal university (2008-2012)

PUBLICATIONS
● Dan Zhao, Xiao-Qing Yi, Jia-Qi Xu, Quan Zhang, Gong-Dao Yuan, Ren-Xi Zhuo, and Feng Li, Self-Hided Nanoparticles Based on Host-Guest Interaction for Targeting Drug Delivery and Reversing Drug Resistant. J. Mater. Chem. B., 2017, 5, 2823-2831.
● Dan Zhao, Xiao-Qing Yi, Gong-Dao Yuan, Ren-Xi Zhuo, and Feng Li, Design and Construction of a Smart Targeting Drug Delivery System Based on Photo-Triggered Competition of Host-Guest Interaction. Macromol. Biosci., 2017, 17, 1700150.
● Dan Zhao, Shu-Jie Ma, Xiao-Qing Yi, Si-Xue Cheng, Ren-Xi Zhuo, and Feng Li, Reversible core-crosslinked nanocarriers with pH-modulated targeting and redox-controlled drug release for overcoming drug resistance. J. Mater. Chem. B., 2017, 5, 8399-8407.
● Dan Zhao, Jia-Qi Xu, Xiao-Qing Yi, Quan Zhang, Si-Xue Cheng, Ren-Xi Zhuo, and Feng Li, pH-Activated Targeting Drug Delivery System Based on the Selective Binding of Phenylboronic Acid, ACS Appl. Mater. Interfaces, 2016, 8, 14845.

Ph. D, Dan Zhao

Postdoc

GRADUATED STUDENTS

Ph.D, Candiates

EDUCATION
● Ph.D & Master, Huazhong University of Science and Technology (2015-   )
● B. Sc., Huazhong University of Science and Technology (2011-2015)



PUBLICATIONS
​​● Nie, C.; Zhang, B.; Gao, Y.; Yin, M.; Yi, X.; Zhao, C.; Zhang, Y.; Luo, L.; Wang, S., Thickness-Dependent Enhancement of Electronic Mobility of MoS2 Transistors via Surface Functionalization. The Journal of Physical Chemistry C 2020, 124 (31), 16943-16950.

​​● Tian, S.; Li, H.; Li, Z.; Tang, H.; Yin, M.; Chen, Y.; Wang, S.; Gao, Y.; Yang, X.; Meng, F.; Lauher, J. W.; Wang, P.; Luo, L., Polydiacetylene-based ultrastrong bioorthogonal Raman probes for targeted live-cell Raman imaging. Nature Communications 2020, 11 (1), 81:1-9.

​​● Xin, Y.; Yin, M.; Zhao, L.; Meng, F.; Luo, L., Recent progress on nanoparticle-based drug delivery systems for cancer therapy. Cancer Biol Med 2017, 14 (3), 228-241.

Mingming Yin

EDUCATION
● Ph.D & Master, Huazhong University of Science and Technology (2016-    )
● B. Sc., Huazhong University of Science and Technology (2012-2016)

PUBLICATIONS
●    Xin, Y.; Wang, S.; Liu, H.; Ke, H.; Tian, S.; Cao, Y.; Huang, Y.; Shang, Y.; Jia, H.; Su, L.; Yang, X.; Meng, F.*; Luo, L.*; “Hierarchical Vitalization of Oligotyrosine in Mitigating Islet Amyloid Polypeptide Amyloidogenesis through Multivalent Macromolecules with Conformation-Restrained Nanobody Ligands”, ACS Nano, 2021

●  Xin, Y.; Zhang, H.; Hu, Q.; Tian, S.; Wang, C.; Luo, L.; Meng, F., Oligotyrosines Inhibit Amyloid Formation of Human Islet Amyloid Polypeptide in a Tyrosine-Number-Dependent Manner. Acs Biomater Sci Eng 2019, 5 (2), 1092-1099.

●  Xin, Y.; Wang, X.; Luo, L.; Meng, F., Conformation-Dependent Manipulation of Human Islet Amyloid Polyp-eptide Fibrillation by Shiitake-Derived Lentinan. ACS Appl Mater Interfaces 2018, 10 (37), 31069-31079.

●  Xin, Y.; Yin, M.; Zhao, L.; Meng, F.; Luo, L., Recent progress on nanoparticle-based drug delivery systems for cancer therapy. Cancer Biol Med 2017, 14 (3), 228-241.

Yanru Xin

EDUCATION
● Ph.D & Master, Huazhong University of Science and Technology (2016-    )
● B. Sc., Huainan Normal University (2012-2016)

PUBLICATIONS
● Zhao, L.; Xin, Y.; Li, Y.; Yang, X.; Luo, L.; Meng, F., Ultraeffective Inhibition of Amyloid Fibril Assembly by Nanobody–Gold Nanoparticle Conjugates. Bioconjugate Chem 2019, 30 (1), 29-33.

● Xin, Y.; Yin, M.; Zhao, L.; Meng, F.; Luo, L., Recent progress on nanoparticle-based drug delivery systems for cancer therapy. Cancer Biol Med 2017, 14 (3), 228-241.

Liyuan Zhao

EDUCATION
● Ph.D & Master, Huazhong University of Science and Technology (2017-   )
● B. Sc., Huazhong University of Science and Technology (2013-2017)

PUBLICATIONS
●  Tian, S.; Yue, Q.; Liu, C.; Li, M.; Yin, M.; Gao, Y.; Meng, F.; Tang, B.*; Luo, L.* “Complete Degradation of a Conjugated Polymer into Green Upcycling Products by Sunlight in Air”, Journal of the American Chemical Society, 2021, 143, 27, 10054–10058

● Yue, Q.; He, X.; Yan, N.; Tian, S.; Liu, C.; Wang, W.-X.; Luo, L.; Tang, B. Z., Photodynamic control of harmful algal blooms by an ultra-efficient and degradable AIEgen-based photosensitizer. Chemical Engineering Journal 2021, 417.

● Liu, C.; Wang, X.; Liu, J.; Yue, Q.; Chen, S.; Lam, J. W. Y.; Luo, L.; Tang, B. Z., Near-Infrared AIE Dots with Chemiluminescence for Deep-Tissue Imaging. Adv Mater 2020, e2004685:1-6.

Qiang Yue

EDUCATION
● Ph.D & Master, Huazhong University of Science and Technology (2017-   )
● B. Sc., Southwest Petroleum University (2013-2017)

PUBLICATIONS
​​● He, Z.; Gao, Y.; Zhang, H.; Wang, X.; Meng, F.; Luo, L.; Tang, B. Z., Platinum-AIEgen coordination complex for imaging-guided annihilation of cisplatin-resistant cancer cells. Chem Commun (Camb) 2020, 56 (56), 7785-7788.
● Gao, Y.; Zhang, H.; He, Z.; Fang, F.; Wang, C.; Zeng, K.; Gao, S.; Meng, F.; Luo, L.; Tang, B. Z., Multicationic AIEgens for unimolecular photodynamic theranostics and two-photon fluorescence bioimaging. Materials Chemistry Frontiers 2020, 4 (6), 1623-1633.
● Wang, X.; Tong, J.; He, Z.; Yang, X.; Meng, F.; Liang, H.; Zhang, X.; Luo, L., Paclitaxel-Potentiated Photodynamic Theranostics for Synergistic Tumor Ablation and Precise Anticancer Efficacy Monitoring. ACS Appl Mater Interfaces 2020, 12 (5), 5476-5487.
● Gao, Y.; He, Z.; He, X.; Zhang, H.; Weng, J.; Yang, X.; Meng, F.; Luo, L.; Tang, B. Z., Dual-Color Emissive AIEgen for Specific and Label-Free Double-Stranded DNA Recognition and Single-Nucleotide Polymorphisms Detection. J Am Chem Soc 2019, 141 (51), 20097-20106.
● Gao, Y.; Wang, X.; He, X.; He, Z.; Yang, X.; Tian, S.; Meng, F.; Ding, D.; Luo, L.; Tang, B. Z., A
Dual‐Functional Photosensitizer for Ultraefficient Photodynamic Therapy and Synchronous Anticancer Efficacy Monitoring. Advanced Functional Materials 2019, 29 (32).

Zhenyan He

EDUCATION
● Ph.D, Huazhong University of Science and Technology (2020-   )
● B. Sc., Huazhong University of Science and Technology (2016-2020)

PUBLICATIONS

​​● Fang, F.; Gao, Y.; Luo, L., Mitochondrion-anchoring AIEgen with Large Stokes Shift for Imaging-guided Photodynamic Therapy. Chemical Research in Chinese Universities 2021, 37 (1), 137-142.
● Gao, Y.; Zhang, H.; He, Z.; Fang, F.; Wang, C.; Zeng, K.; Gao, S.; Meng, F.; Luo, L.; Tang, B. Z., Multicationic AIEgens for unimolecular photodynamic theranostics and two-photon fluorescence bioimaging. Materials Chemistry Frontiers 2020, 4 (6), 1623-1633.
● Fang, F.; Meng, F.; Luo, L., Recent advances on polydiacetylene-based smart materials for biomedical applications. Materials Chemistry Frontiers 2020, 4 (4), 1089-1104.

Fang Fang

EDUCATION
● Ph.D, Huazhong University of Science and Technology (2021-   )
● B. Sc., Huazhong University of Science and Technology (2017-2021)

Jinfeng Lin

Graduated Students

Master Candiates

EDUCATION
● Master, Huazhong University of Science and Technology (2019-   )
● B. Sc., Huazhong University of Science and Technology (2015-2019)

Yuan Lu

EDUCATION
● Master, Huazhong University of Science and Technology (2019-   )
● B. Sc., Huazhong University of Science and Technology (2015-2019)

Zhiyong Zhuang

EDUCATION
● Master, Huazhong University of Science and Technology (2020-   )
● B. Sc., Huazhong University of Science and Technology (2016-2020)

Shaohua Wang

EDUCATION
● Master, Huazhong University of Science and Technology (2020-   )
● B. Sc., Huazhong University of Science and Technology (2015-2019)

Guangxuan Zeng

EDUCATION
● Master, Huazhong University of Science and Technology (2019-   )
● B. Sc., Huazhong University of Science and Technology (2015-2019)

Hongyu Li

EDUCATION
● Master, Huazhong University of Science and Technology (2021-   )
● B. Sc., Henan Univesity (2017-2021)

Sujuan Liu

EDUCATION
● Master, Huazhong University of Science and Technology (2021-   )
● B. Sc., Huazhong Agricultural Univesity (2017-2021)

Minle Zhan

ALUMNI

PUBLICATIONS DURING LUO GROUP

● Nie, C.; Zhang, B.; Gao, Y.; Yin, M.; Yi, X.; Zhao, C.; Zhang, Y.; Luo, L.; Wang, S., Thickness-Dependent Enhancement of Electronic Mobility of MoS2 Transistors via Surface Functionalization. The Journal of Physical Chemistry C 2020, 124 (31), 16943-16950.

● He, Z.; Gao, Y.; Zhang, H.; Wang, X.; Meng, F.; Luo, L.; Tang, B. Z., Platinum-AIEgen coordination complex for imaging-guided annihilation of cisplatin-resistant cancer cells. Chem Commun (Camb) 2020, 56 (56), 7785-7788.

● Gao, Y.; Zhang, H.; He, Z.; Fang, F.; Wang, C.; Zeng, K.; Gao, S.; Meng, F.; Luo, L.; Tang, B. Z., Multicationic AIEgens for unimolecular photodynamic theranostics and two-photon fluorescence bioimaging. Materials Chemistry Frontiers 2020, 4 (6), 1623-1633.

● Hou, Y.; Kurganskii, I.; Elmali, A.; Zhang, H.; Gao, Y.; Lv, L.; Zhao, J.; Karatay, A.; Luo, L.; Fedin, M., Electronic coupling and spin-orbit charge transfer intersystem crossing (SOCT-ISC) in compact BDP-carbazole dyads with different mutual orientations of the electron donor and acceptor. J Chem Phys 2020, 152 (11), 114701.

● Wang, Z.; Ivanov, M.; Gao, Y.; Bussotti, L.; Foggi, P.; Zhang, H.; Russo, N.; Dick, B.; Zhao, J.; Di Donato, M.; Mazzone, G.; Luo, L.; Fedin, M., Spin-Orbit Charge-Transfer Intersystem Crossing (ISC) in Compact Electron Donor-Acceptor Dyads: ISC Mechanism and Application as Novel and Potent Photodynamic Therapy Reagents. Chemistry 2020, 26 (5), 1091-1102.

● Tian, S.; Li, H.; Li, Z.; Tang, H.; Yin, M.; Chen, Y.; Wang, S.; Gao, Y.; Yang, X.; Meng, F.; Lauher, J. W.; Wang, P.; Luo, L., Polydiacetylene-based ultrastrong bioorthogonal Raman probes for targeted live-cell Raman imaging. Nature Communications 2020, 11 (1), 81:1-9。

● Gao, Y.; He, Z.; He, X.; Zhang, H.; Weng, J.; Yang, X.; Meng, F.; Luo, L.; Tang, B. Z., Dual-Color Emissive AIEgen for Specific and Label-Free Double-Stranded DNA Recognition and Single-Nucleotide Polymorphisms Detection. J Am Chem Soc 2019, 141 (51), 20097-20106.

● Gao, Y.; Wang, X.; He, X.; He, Z.; Yang, X.; Tian, S.; Meng, F.; Ding, D.; Luo, L.; Tang, B. Z., A Dual‐Functional Photosensitizer for Ultraefficient Photodynamic Therapy and Synchronous Anticancer Efficacy Monitoring. Advanced Functional Materials 2019, 29 (32),1902673.

● Wang, Z.; Gao, Y.; Hussain, M.; Kundu, S.; Rane, V.; Hayvali, M.; Yildiz, E. A.; Zhao, J.; Yaglioglu, H. G.; Das, R.; Luo, L.; Li, J., Efficient Radical-Enhanced Intersystem Crossing in an NDI-TEMPO Dyad: Photophysics, Electron Spin Polarization, and Application in Photodynamic Therapy. Chemistry – A European Journal 2018, 24 (70), 18663-18675.

Yuting Gao


● Huang, L.; Zhang, Y.; Li, Y.; Meng, F.; Li, H.; Zhang, H.; Tu, J.; Sun, C.; Luo, L., Time-Programmed Delivery of Sorafenib and Anti-CD47 Antibody via a Double-Layer-Gel Matrix for Postsurgical Treatment of Breast Cancer. Nanomicro Lett 2021, 13 (1), 141.
● Wang, X.; Huang, L.; Zhang, Y.; Meng, F.; Donoso, M.; Haskell, R.; Luo, L., Tunable Two-Compartment On-Demand Sustained Drug Release Based on Lipid Gels. J Pharm Sci 2020, 109 (2), 1059-1067.
● Huang, L.; Li, Y.; Du, Y.; Zhang, Y.; Wang, X.; Ding, Y.; Yang, X.; Meng, F.; Tu, J.; Luo, L.; Sun, C., Mild photothermal therapy potentiates anti-PD-L1 treatment for immunologically cold tumors via an all-in-one and all-in-control strategy. Nature Communications 2019, 10 (1).

PUBLICATIONS DURING LUO GROUP

Liping Huang

Postdoctor


​​● Liu, C.; Wang, X.; Liu, J.; Yue, Q.; Chen, S.; Lam, J. W. Y.; Luo, L.; Tang, B. Z., Near-Infrared AIE Dots with Chemiluminescence for Deep-Tissue Imaging. Adv Mater 2020, e2004685:1-6.
● Wang, X.; Huang, L.; Zhang, Y.; Meng, F.; Donoso, M.; Haskell, R.; Luo, L., Tunable Two-Compartment On-Demand Sustained Drug Release Based on Lipid Gels. J Pharm Sci 2020, 109 (2), 1059-1067.
● Wang, X.; Tong, J.; He, Z.; Yang, X.; Meng, F.; Liang, H.; Zhang, X.; Luo, L., Paclitaxel-Potentiated Photodynamic Theranostics for Synergistic Tumor Ablation and Precise Anticancer Efficacy Monitoring. ACS Appl Mater Interfaces 2020, 12 (5), 5476-5487.
● Gao, Y.; Wang, X.; He, X.; He, Z.; Yang, X.; Tian, S.; Meng, F.; Ding, D.; Luo, L.; Tang, B. Z., A Dual‐Functional Photosensitizer for Ultraefficient Photodynamic Therapy and Synchronous Anticancer E-fficacy Monitoring. Advanced Functional Materials 2019, 29 (32).
●  Xin, Y.; Wang, X.; Luo, L.; Meng, F., Conformation-Dependent Manipulation of Human Islet Amyloid Polypeptide Fibrillation by Shiitake-Derived Lentinan. ACS Appl Mater Interfaces 2018, 10 (37), 31069-31079.

PUBLICATIONS DURING LUO GROUP

Xiuxia Wang

Doctor

Master, Yujuan Cao

Master, Huimin Zhang

Master, Yujuan Cao

Master, Yiyi Zhang

Master, Yujuan Cao

Master, Yujuan Cao

Master, Qigang Hu

Master, Yanan Li

Master, Xiang Yang

Master