Wuhan · China
Welcome to Liang Luo Group
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Research Interest
In our lab, we focus on the design, preparation, and biomedical application of conjugated polymers. In particular, we are interested in applying these materials in biomedical imaging and disease therapies.
1.Exploring new conjugated polymer materials to enhance the efficiency of Raman imaging, fluorescence imaging, and CT imaging, so as to improve the performance of these techniques in precision tumor radiotherapy, chemotherapy, and surgery.
2.Developing novel drug delivery systems to integrate the outstanding optoelectronic properties of conjugated polymer materials for the diagnosis and treatment of diseases such as cancer, Alzheimer’s disease, and bowel disorders.
3.Degradable polymer materials.
4.Emerging properties and mechanisms of conjugated polymer materials.
1. D. Zhang, S. Tian, Y. Liu, M. Zheng, X. Yang, Y. Zou*, B. Shi*, L. Luo*. Near infrared-activatable biomimetic nanogels enabling deep tumor drug penetration inhibit orthotopic glioblastoma. Nature Communications. 2022, 13, 6835.
2. Y. Zhang, S. Tian, L. Huang, Y. Li, Y. Lu, H. Li, G. Chen, F. Meng, Gang L. Liu, X. Yang, J. Tu, C. Sun, L. Luo*. Reactive oxygen species-responsive and Raman-traceable hydrogel combining photodynamic and immune therapy for postsurgical cancer treatment. Nature Communications. 2022, 13, 4553.
3. M. Yin, X. Liu, Z. Lei, Y. Gao, J. Liu, S. Tian, Z. Liang, Y. Wang, F. Meng, L. Luo*. Precisely translating computed tomography diagnosis accuracy into therapeutic intervention by a carbon-iodine conjugated polymer. Nature Communications. 2022, 13, 2625.
4. S. Tian, Q. Yue, C. Liu, M Li, M. Yin, Y. Gao, F. Meng, B. Z. Tang*, L. Luo*. Complete degradation of a conjugated polymer into green upcycling products by sunlight in air. Journal of the American Chemical Society, 2021, 143, 10054.
5. S. Tian, H. Li, Z. Li, H. Tang, M. Yin, Y. Chen, S. Wang, Y. Gao, X. Yang, F. Meng*, J. W. Lauher*, P. Wang*, L. Luo*. Polydiacetylene-based ultrastrong bioorthogonal Raman probes for targeted live-cell Raman imaging. Nature Communications. 2020, 11, 81.
Prof. Liang Luo